Providing every conceivable chance of success for 38 years
At CRM, we provide our patients with first-class treatment and attentive service. We are committed to providing care that is genuine and compassionate, and our IVF success rates exceed the national delivery rate in every category.

New Patients
Supporting and educating new patients
We provide new patients with the tools and resources to make informed decisions. Learn more about initial infertility evaluations, our team, and find answers to your questions.

Current Patients
Patient Resources and Support
Infertility care is deeply personal, and we work to make the experience as comfortable and straightforward as possible. Use this page to access key resources—including forms, the patient portal, payments, FAQs, and injection videos—to help you stay informed and supported throughout treatment.
Egg Donation:
The Gift of Family
As the premier provider of IVF in the Twin Cities, we’re proud to offer one of the most successful donor egg programs available today. Patients and donors can participate in advanced reproductive therapy procedures with proven outcomes and exceptional support.

IUI
Intrauterine
Insemination (IUI)
IUI increases the number of sperm that reach the eggs in the fallopian tubes, at the appropriate time. This increases your chances of getting pregnant.
IVF
In Vitro
Fertilization (IVF)
IVF is an assisted reproductive technology where eggs are fertilized by sperm in a lab and then placed in the uterus to help achieve pregnancy.
Patient Testimonies
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“We are beyond grateful for Dr. Joshua D. Kapfhamer, who has been a true blessing on our journey to parenthood. From the very beginning, Dr. Kapfhamer showed compassion, expertise, and dedication that immediately put us at ease. He helped us welcome our first IVF baby into the world, and we’re now on our way to our second miracle, thanks to his unwavering support and skill.”
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“We just got home with our newborn son, who we have thanks to IVF at CRM. We went through several IUIs and two IVF implantations. It took a couple of years, but here we are. The staff was almost always great and the clinic is clean and comfortable. We worked with Dr. Casey who was always supportive and willing to take extra time to explain things to us. Our son is beautiful. Thanks CRM.”
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“Dr. Kapfhamer took the time to thoroughly explain every step of the process, answer all our questions, and ensure we felt informed and confident along the way. His calm, reassuring presence was invaluable during moments of doubt or anxiety. The level of care and attention we received from him and his team has been outstanding, and it’s clear that he truly cares about his patients’ success.”
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“Many of us end up at CRM after we’ve lost trust in our bodies ability to do what we think it should, or when we’ve lost faith we can achieve our reproductive goals. It can be scary going somewhere unknown for something we haven’t experienced before that a lot of people are private about their experiences with. In my experience, CRM made me feel really safe when I’d started losing faith. Everyone at CRM made me feel heard, understood, and taken care of. By everyone I mean the staff who answer your calls, the office staff, the ultrasound techs and phlebotomists, the embryologists/lab staff, finance folks, and of course the doctors and nurses. They all make the emotional processes of evaluating, diagnosing, treating/plan implementing, and, in our case, achieving a successful pregnancy via IVF, as pleasant an experience as I can imagine. One you can figure out. One you can handle. One that in my experience you won’t ever have wished you started later than you did.”
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“I recently had the privilege of attending a new patient consultation with Dr. Hopeman, a renowned IVF specialist, and the experience was nothing short of exceptional. From the moment I walked into her office, I could sense her genuine care and dedication to her patients’ well-being. Dr. Hopeman’s willingness to take the time to thoroughly explain the entire IVF procedure was truly commendable. She left no stone unturned, providing a detailed overview of each step, the potential challenges we might face, and the success rates associated with various approaches. Her expertise was evident, and she effortlessly demystified the complex process, leaving me feeling much more informed and reassured.”
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“We loved the staff at CRM. They were always responsive and helpful. I couldn’t imagine having better people helping us through our process. As an LGBT couple, the clinic made us feel welcome. The entire nursing staff is amazing. Highly recommend.”
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“Dr. Damario is the very best. He took our infertility seriously with fresh eyes to solve confusing test results that other infertility doctors did not. We will be forever grateful he unlocked the success for our family to grow.”

100% Refund
Successful treatment means having a baby. Patients willing to commit to multiple IVF cycles can dramatically increase their chances of success.
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Colleen L. Casey, M.D., President
Meet Colleen“I entered college with an interest in journalism but during my second year of college I began working in the medical school and changed my major to zoology with a minor in women’s studies. This put me on the path toward human medicine, with an emphasis on women’s health.”
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Mark A. Damario, M.D., Medical Director
Meet Mark“Different people choose a career in medicine for different reasons. I loved the science of it and wanted to help people in need. For me, it is a privilege to be working in a reproductive medicine practice that focuses on achieving the best outcomes for patients who want to have children.”
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Meg M. Hopeman, M.D.
Meet Meg“What I have found most compelling about reproductive endocrinology is that it is not just practicing medicine – it’s helping patients to overcome conditions on their journey to grow their family and community. The opportunity to play a supporting role in your life’s village is an honor I absolutely cherish””
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Joshua D. Kapfhamer, M.D., MA
Meet Joshua“Infertility is a deeply personal and emotional experience for nearly all who must face it. I do not take this lightly and consider it an honor to be entrusted with the responsibility of guiding my patients along their journey, no matter what the circumstances.”
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Douglas T. Carrell, Ph.D., H.C.L.D., Laboratory Director
Meet Douglas“As an undergraduate, I was looking for a field of study with both interesting science research as well as quality patient care. I was attracted to this area because the lab work was both challenging and rewarding as well as a fascinating area of research. I am very involved in research on how the sperm influences embryo growth.”
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Rachel B. Mejia, D.O.
Meet Rachel“One of the foundations of patient care is building trust and having open, honest conversations. I want to really understand each patient’s goals and values so we can create a care plan that feels personal, supportive, and right for their journey.”
Inclusive care for all families
No two families are alike, and we’re proud to support families of every kind. Whether you’re an LGBTQ+ couple, a single parent by choice, or a couple growing your family, our team will help you explore the options that fit your family.
Years in Minneapolis
Total Annual Transfers
1 of 4
Andrology Labs in MN

News and Articles
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Lighting the Way Through Infertility
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Exciting Changes Ahead: Our Clinic Refresh Journey
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Understanding Egg Donation: Help Create A Pathway to Parenthood
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Enhancing Patient Care: CRM’s New Partnerships with Engaged MD and Cloud RX
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Addressing the Underrepresentation of Asian Women as Egg Donors
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Single Parenting Options by Choice (SPBC)
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Patient IVF Story: Katie Warner
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We’re Lighting it Up Orange
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Does Your Clinic Recommend A Single or Double Embryo Transfer?
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How Does Age Affect Fertility?
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Watch Dr. Kapfhamer On KARE11
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Dr. Colleen Casey appearance on “This is Infertility” Podcast
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CRM Nurses Recertified By ASRM
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A Prestigious Honor For Douglas T. Carrell
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Maximizing Your Andrology Care
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The “White Face of Infertility”
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Finding Donors Can Feel Like a Minefield
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CRM’s Small Talk Survival Guide
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Fertility’s “Michelle Obama Effect” Is in Full Swing
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CRM Andrology: The Who, What, When, and Why Of It
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Egg Freezing: Still In The News
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Socks: A Gift That Gets Better With Age
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Infertility Doesn’t Take The Summer Off
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The Center for Reproductive Medicine: A Legacy of Education, Inclusivity and Choice (via MDNews)
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Jean Purdy’s Recognition Is Long Overdue
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Looking At Infertility Through Male Eyes
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What’s Not To Love About Mother’s Day?
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#InfertilityUncovered- April 21-27 Is National Infertility Awareness Week
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Lawyers Are Putting Their Fertility On Ice
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Military Women: On the Hook for Infertility?
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VIDEO: Michelle Obama & Exploring Your Fertility
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Infertility Makes Its Way to Netflix
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Egg Freezing In The News
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ASRM Certification: A New Era At CRM
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The Heat of Summer Is a Great Time to Think About Freezing
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Does “You Are What You Eat” Apply to Fertility?
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Infertility Doesn’t Take a Summer Vacation
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Mother’s Day Is a Day of Mixed Emotions for Many
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#FlipTheScript – National Infertility Awareness Week
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Let’s Take a Closer Look at Male Infertility
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CRM’s Reproductive Endocrinologist Joins The Paul & Jordana Show
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Donor Egg Treatment: One Patient’s Story
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40th Anniversary of First IVF Baby: What Does The Future Hold For IVF?
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Therapeutic Donor Insemination: What You Need to Know
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How to Support Your Spouse When Going Through Infertility
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IVF Cost: What to Consider Before Choosing Your Clinic
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Choosing a Fertility Clinic in Minnesota: What to Look For
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Evaluating Men’s Fertility
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National Women’s Health Week: Healthy Steps You Can Take to Help You Conceive
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National Infertility Awareness Week
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National Endometriosis Awareness Month
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Common Misconceptions About Infertility
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How Folic Acid Can Help You
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Crohn’s Disease and Your Fertility
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Testing for Infertility
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The Effects of Cancer Treatment on Your Fertility
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Proper Nutrition for Conception
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10 Fertility Terms You Need to Know
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Advancements in In Vitro Fertilization
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Men’s Health Month: Boosting Male Fertility
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Helping You Achieve a Healthy Pregnancy
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World Immunization Week: The Importance of Immunizations
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National Infertility Awareness Week: We’re Here for You
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Common Misconceptions About Fertility
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National Endometriosis Awareness Month: Does Endometriosis Affect Your Fertility?
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Zika Virus: What You Need to Know
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Polycystic Ovary Syndrome and Fertility
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Factors That Affect Fertility
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Understanding Fertility Medication
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Are You a Candidate for IVF?
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Is Egg Freezing for You?
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Planning for Pregnancy: Preconception Tips
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Tips to Boost Your Fertility
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When is PGT Right For You?
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Center for Reproductive Medicine’s Team Voted 2015 Best Doctors for Women
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Fertility Testing: What You Need To Know
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